In regards to ESPN mentioning "Knucklehead" as an MMA movie, the WWE.com article that they have about the production wrapup mentions the following:
"Written by Tom Sullivan & Bear Aderhold and Adam Rifkin, “Knucklehead” follows the on-the-road adventures of a trio of misfits – a naïve giant and church orphan-turned-amateur fighter Walter Krunk (Big Show); former mixed martial arts champion-turned-manager Eddie Sullivan (Mark Feuerstein); and church aide-turned-chaperone, Mary O’Connor (Melora Hardin) – fighting their way across the south to the annual Pro-Am mixed martial arts tournament in New Orleans."
So, the script has been changed from Show as a professional wrestler to a "MMA fighter."